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How to naturally raise tetrahydrobiopterin (BH4)
Actually, L‑Tryptophan travels down several very beneficial pathways. Most-importantly, though, to sufferers of insomnia, depression and eating disorders, if all the proper cofactors/coenzymes are present, L‑Tryptophan travels from the blood stream to serotonin-sensitive neurons where it converts to serotonin. Brain messages of satiety (fullness) and well-being can then be sent without interruption. On the other hand, if certain enzymes are inactive – due to a lack of cofactors and coenzymes – L‑Tryptophan can be diverted down the kynurenine pathway and converted to niacin or to the mildly-toxic quinolinic acid.
For the scientists among you… inside the serotonin-sensitive neuron, L‑Tryptophan and tetrahydrobiopterin (abbreviated BH4) combine to form 5-Hydroxy L‑Tryptophan, the first step in the L‑Tryptophan-to-serotonin pathway. Well-funded researchers in university laboratories have found that BH4 actually increases the flow down the serotonin pathway. Although it doesn’t take much BH4, the astronomical cost of $4 million per kilogram will keep BH4 out of the reach of nutritional supplements. Fortunately, the researchers at LIDTKE have found a combination of nutrients that increases the natural levels of BH4 at a far more affordable price.
The second step to serotonin production requires Vitamin B6… but not just any, cheap Pyridoxine Hydrochloride (HCl) will do the job. Serotonin-producing enzymes can only use Vitamin B6 in the form of Pyridoxal 5-Phosphate (P5P). While pure P5P costs far less than $4 million per kilogram, it is still ten times more expensive than the Pyridoxine HCl usually found in nutritional supplements.
Although most individuals can convert some dietary Pyridoxine HCl to P5P, knowledgeable researchers have voiced concern that incompletely converted Pyridoxine HCl may actually block the benefits of the true form of vitamin B6. Hence, LIDTKE L‑Tryptophan Complete uses only genuine Pyridoxal 5-Phosphate, the kind your body uses.
In short, the full complex of cofactors and coenzymes included in L‑Tryptophan Complete maximizes the conversion of L‑Tryptophan to serotonin, but at LIDTKE that is not enough. Very recent research shows that curcumin, the same curcumin that reduces cancer risk in experimental animals, also helps reduce the breakdown of serotonin into inactive metabolites. Curcumin in L‑Tryptophan Complete, then, helps ensure that the serotonin your body creates will be available when your body needs it.
L‑Tryptophan Complete maximizes serotonin both coming and going. By increasing production of serotonin directly within serotonin-sensitive neurons and by reducing the break-down of serotonin, L‑Tryptophan Complete becomes a powerful, fast-acting agent for the relief of insomnia, depression, anxiety and a multitude of stress-induced maladies of our age. Whether you are overcome by the stresses of home or the business world, whether your individual biochemistry is ideal or whether you suffer from an imbalance, L‑Tryptophan Complete is the finest answer on the market. Feel better, sleep better. Be at peace in body, mind and spirit.
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